The healing properties of cannabis have been known for thousands of years.
Cannabis has been used for medical purposes as a treatment for 3,000 years in various cultures. Historical evidence suggests that doctors have been mixing cannabis with various medicines to treat pain and other ailments.
Today, cannabis finds application in a wide range of medical conditions, with its medicinal use being mainly associated with relieving from physical and mental difficulties, as well as keeping the body in balance.
Medicinal cannabis is used among others for, for reduceing spasticity in patients with multiple sclerosis,and it is indicated for the prevention and treatment of nausea and / or hyperemesis due to chemotherapy, . Moreover, it contributes to the treatment of chronic neuropathic pain and the palliative care of patients in the final stages of cancer.
Τhe use of medicinal cannabis was legalized in Greece, in 2017, while in March 2018, the legal framework was created for its cultivation, processing, marketing and export. Currently, the production and distribution of finished medicinal cannabis products with a tetra-hydrocannabinol (THC) content of more than 0.2% is allowed for purely medical purposes either internally or for export. The mode of action of formulations containing cannabinoids is based on the physiological mechanisms of the Endocannabinoid System (ECS).
It is a complex network of receptors, signaling molecules (endocannabinoids) and enzymes. ECS was discovered rather recently. Although the molecules of THC and CBD (phytocannabinoids) have been isolated as early as the 60s and their structures have been elucidated by Dr. Raphael Mechoulam, the mechanism through which these molecules exerted their action remained unknown. It was not until 1988, that it was found that the brain of mammals express receptors which respond to cannabis components. A few years later, the receptors CB1 and CB2 of the ECS were cloned, while in 1992, the endocannabinoid molecule anandamide was isolated for the first time, once again from the laboratory of Dr. Mechoulam. Dr. Mechoulam's findings were the starting point for scientific research and clinical studies on the therapeutic uses of the cannabis plant and served as the scientific basis for the establishment of Tikun Olam in 2002.
Regarding the role of the ECS, well-established evidence shows that it plays an important role in human health and well-being. It serves the essential function of restoring homeostasis through physiological and regulatory mechanisms. Its effectiveness is enhanced by the intake of cannabinoids and their interaction with the ECS receptors. The beneficial effect of cannabinoids is supported by a large number of bibliographic references. Cannabinoids potentially help relieve pain, manage stress, improve mood, increase appetite and energy. In addition, they help reduce nausea and enhance the immune system.
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A non-psychoactive, non-addictive substance which belongs to the main cannabinoid family.
CBD is associated with beneficial outcomes that support balance and well-being and helps in everyday discomforts.
It is used any time of the day.
Tikun Olam based in Israel is a proud pioneer and global leader in medical cannabis research. Rooted in Israel's regulatory environment, Tikun Olam’s team of scientists have been studying medical cannabis and performing clinical trials for more than a decade, achieving outstanding results and amassing one of the world's largest database of patients under medical cannabis treatment numbering currently more than 20,000 patients.
Through extensive research and development, Tikun Olam's proprietary strains have been genetically optimized and clinically proven to provide symptomatic relief for a wide variety of ailments, including nausea/ hyperemesis from chemotherapy, neuropathic and chronic pain, spasticity in MS and more. Achievements on the clinical field have encouraged Tikun to devote additional resources to further improve its products, as well as to better understanding of the therapeutic properties of the cannabis plant.
Tikun conducts laboratory studies (both in vitro and in vivo), retrospective analyses, and clinical trials, and works diligently to follow-up with patients.
Tikun Olam Europe’s medical cannabis is grown using high-level scientific techniques. It owns the exclusive use of award-winning strains that have been genetically modified to maximize symptomatic relief. Specifically for the development of its medical formulations, Tikun Olam Europe has selected, from a range of Tikun Olam Israel cannabis strains, the ones that cover the widest range of medical conditions for which there is documented efficacy, based on clinical studies.
Tikun Olam Europe’s medical cannabis is grown using high-level scientific techniques. It owns the exclusive use of award-winning strains that have been genetically modified to maximize symptomatic relief. Specifically for the development of its medical formulations, Tikun Olam Europe has selected, from a range of Tikun Olam Israel cannabis strains, the ones that cover the widest range of medical conditions for which there is documented efficacy, based on clinical studies.
